OBC: Contents

The chick embryo – past, present and future as a model system in developmental biology 1011 PART I: The chick as a classical system for the study of development L. Wolpert (UK) Much more from the chicken's egg than breakfast – a wonderful model system 1015 C. Tickle (UK) The contribution of chicken embryology to the understanding of vertebrate limb development 1019 L. Wittler, M. Kessel (Germany) The acquisition of neural fate in the chick 1031 A. Raya, J.C. Izpisua Belmonte (USA) Unveiling the establishment of left–right asymmetry in the chick embryo 1043 Somite polarity and segmental patterning of the peripheral nervous system 1055 O. Pourquié (USA) The chick embryo: a leading model in somitogenesis studies 1069 A. Lumsden (UK) Segmentation and compartition in the early avian hind-brain 1081 N.M. Le Douarin (France) The avian embryo as a model to study the development of the neural crest: a long and still ongoing story 1089 S.R. Price, J. Briscoe (UK) The generation and diversification of spinal motor neurons: signals and responses 1103 F. Dieterlen-Lièvre, N.M. Le Douarin (France) From the hemangioblast to self-tolerance: a series of innovations gained from studies on the avian embryo 1117 PART II: New technologies and future prospects D.W. Burt (UK) The chicken genome and the developmental biologist 1129 Gain-and loss-of-function in chick embryos by electro-poration 1137 Efficient identification of regulatory sequences in the chicken genome by a powerful combination of embryo electroporation and genome comparison 1145